Lipase

Lipase is a digestive enzyme that plays a crucial role in the digestion and metabolism of dietary fats. It is responsible for breaking down triglycerides, the main form of fat, into smaller components like fatty acids and glycerol. This breakdown allows for easy absorption and utilization by the body.

Lipase supplementation can have several health effects. Firstly, it can support digestion in individuals with pancreatic insufficiency, a condition where the pancreas does not produce enough lipase and other enzymes. Lipase supplements can help break down fats and improve fat absorption, thereby aiding in digestion.

Secondly, lipase supplementation may benefit individuals with fat malabsorption disorders, such as cystic fibrosis or certain gastrointestinal diseases. These conditions can impair the absorption of fats, leading to deficiencies of essential fatty acids and fat-soluble vitamins. Lipase supplements can assist in breaking down fats and improving nutrient absorption in these cases.


References:

Levine, Max E., et al. "Lipase Supplementation before a High-Fat Meal Reduces Perceptions of Fullness in Healthy Subjects." Gut Liver, vol. 9, no. 4, 2015, pp. 464-469. doi: 10.5009/gnl14005.

Park, Seon-Young, and Jong-Sun Rew. "Is Lipase Supplementation before a High Fat Meal Helpful to Patients with Functional Dyspepsia?" Gut Liver, vol. 9, no. 4, 2015, pp. 433-434. doi: 10.5009/gnl15206.